Hey Steve, thanks for using the forum!
I think the most straightforward job is to perform a turbine simulation, with only one fluid phase (air in this case) and applying the known pressure or flow rate as input for the boundary conditions.
A rigid body motion of the turbine (rotation) driven by the flow is hard to do, and the standard approach is to use a rotating region at the operation point, then assess the efficiency of the turbine.
You would perform a simulation similar to the one shown in this tutorial:
So please try to grab the concept of the model and the setup and apply it to your case. If you have a project in the platform with your CAD, please share the link to also have a look at it.